HORDB

ID: hor002360
Uniprot ID: P15513??358-364)
Protein name: Myomodulin-F
Gene name: MYOMOD1
Organism: Aplysia californica (California sea hare)
Family: Myomodulin family
Source: animal
Expression: Expressed in all ganglia of the CNS, but only in a subset of neurons including L10 in the abdominal ganglion and B16 in the buccal ganglion.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: SLNMSRL
Length: 7(358-364)
Propeptide: MQVYMLLPLAVFASLTYQGACEETAAAQTSSDASTSSASSEHAENELSRAKRGSYRMMRLGRGLHMLRLGKRGGPVEPESEENLETLLNLLQGYYSDVPEYPSEFDDTDLAYPYEEYDAPAHPRYRRSTPPTDGVVAPDVLQKGSSEFEDFGDSQLDESDEGYYGYDPENYLYGDFEDYLEPEEGGLGEEKRSLSMLRLGKRGLSMLRLGKREGEEGDEMDKKQDESLNDDFENDDIKRTLSMLRLGKRPMSMLR
Signal peptide: MQVYMLLPLAVFASLTYQ
Modification: T7 Leucine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002360_AF2.pdb

hor002360_ESM.pdb

Mass:	92717	Formula:	C33H61N11O11S
Absent amino acids:	ACDEFGHIKPQTVWY	Common amino acids:	LS
pI:	10.55	Basic residues:	1
Polar residues:	3	Hydrophobic residues:	2
Hydrophobicity:	-1.43	Boman Index:	-1617
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	111.43
Instability Index:	9885.71	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 7472354
Title: Nine Members of the Myomodulin Family of Peptide Cotransmitters at the B16-ARC Neuromuscular Junction of Aplysia